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Novel Prodrugs for Selective Anticancer Therapy

Novel methods to make anticancer prodrugs by conjugating unique dual-substrate biochemical modules to known or novel chemotherapeutic drugs Background: Anticancer drug sales exceeded $50 billion worldwide in 2009 with impressive growth; however, lack of target selectivity is a major challenge in cancer treatment. The limitation of current chemotherapy...
Published: 11/22/2023   |   Inventor(s): Michael Hayman, Nobuhide Ueki
Keywords(s): anticancer drugs, cancer-associated protease, HDAC, nucleoside analogues, Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Drug Delivery, Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Therapeutics

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