A Nanocomposite Scaffold Consisting of Functionalized Gold Particles and Nanofibrous Membranes for Fabrication of Flexible Sensors

Novel nanoparticle sensor with applications in sweat detection for medical monitoring. Background: Perspiration contains useful medical information on physical conditions for those living in environments with high temperatures, or for those who engage in physical activity for extended periods of time. Because of this, there has been an increase in demand for the development of wearable sweat sensors. Progress has been made thus far, but challenges are present, such as lack of multifunctionality, biocompatibility, and flexibility. Also, they're high-cost and have insufficient sensitivity. Technology Overview: This technology consists of assembling functional nanoparticles within nanofibrous membranes in order to construct composite materials having adjustable, multifunctional, and flexible properties. One implementation describes a nanocomposite scaffold derived from the assembly of gold nanoparticles in a nanofibrous membrane with multiple layers. This happens through controlled interactions. The preferred embodiment is a three layer nanofiber membrane including cellulose nanofibers, cross-linked polyethylene glycol diacrylate, and nonwoven polyethylene terephthalate. Advantages: Sensors can be made for specific substances (i.e. ions, solutes, reagents) - Flexible, multifunctional, tunable, and biocompatible - device flexibility and wearability - Low-cost manufacturing Applications: -Biological fluid sensors

-Biomarker secretion sensors

-Permeation of water Intellectual Property Summary: Patent application submitted Stage of Development: Licensing Potential: Development partner,Commercial partner,Licensing Licensing Status: Available for licensing. R-8891 Additional Information: membrane,fluid sensors,perspiration,sweat,biocompatibility,nanocomposite,polyethylene terephthalate,biocompatible,permeation,nanotechnology,sensor,fibrous scaffold,gold nanoparticle,nanofiber,nanofibre,nanoparticle,wearable,nanoparticles,sensors,wearables,gold nanoparticles,3g,nanofibers,sweat analysis,medical sensor,wearable sensor,wearable medical device,biological fluid sensor,fluid sensor https://stonybrook.technologypublisher.com/files/sites/zlz2m25lr3awhywfvetf_r-8891-5598159209_0bfa61cb10_o-flickr-kullez-cc-by-2.0.jpg Header image is purely illustrative. Source: Kullez/Flickr, https://www.flickr.com/photos/kullez/5598159209, CC BY 2.0.

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