Nanosphere Delivery System for the Treatment of Spinal Cord Injury

SUNY Upstate Medical University researchers have developed a controlled-released treatment for delivering a nerve repair drug precisely to areas of damage. With traumatic spinal cord injury or the neurodegenerative disease multiple sclerosis, demyelination of nerve cells lead to loss of motor function. The compound chondroitinase (cABC) boosts the body’s own repair mechanism, but its success as a treatment requires releasing the drug at the damage site over an extended period of time. SUNY doctors have developed biocompatible and biodegradable cABC-containing nanospheres that can be injected near sites of injury where they remain until degraded away, gradually releasing the treatment drug for up to two weeks. Experiments have shown regeneration of damaged nerves.  More...

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