Monoclonal Antibody, Anti Ft LVS DnaK Clone 193

A Francisella tularensis infection-derived monoclonal antibody for use in detecting infectious diseases and bioterrorism related to tularemia. Background: Francisella tularensis is an intracellular, gram-negative bacterium that primarily invades macrophages and attacks the human immune system. Technology Overview: Developed by Jorge. L Benach. Ph.D., director of the Center for Infectious Diseases in the Centers for Molecular Medicine, and chair of the Department of Molecular Genetics and Microbiology at Stony Brook University, this murine, IgG, monoclonalantibody recognizes a native epitope of Francisella tularensis "Live Vaccine Strain"; monoclonal antibody clone 193 against a native epitope of Francisella tularensis protein dnaK. Additional research efforts may reveal this antibody's involvementin the attenuation of bacterial infection. Advantages: The antibody was developed from a mouse infected with F.tularensis live vaccine strain and not recombinant protein, therefore representing a natural antibody made by the mouse in defense of infection against the native F. tularensis protein. Applications: Western blot, ELISA, Immunoprecipitation, Immunofluorescence assays Intellectual Property Summary: Stage of Development: Sample prototypes are available for testing. Licensing Potential: We seek to develop and commercialize, by an exclusive or non-exclusive license agreement and/or sponsored research, with a company active in the area. Licensing Status: Available for License Additional Information: Molecular Genetics and Microbiology Monoclonal antibody, F. tularensis LVS, dnaK ,
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