Infection-derived monoclonal antibody for use in detecting infectious diseases and bioterrorism related to tularemia.
Francisella tularensis is an intracellular, gram-negative bacterium that invades macrophages and attacks the human immune system.Tuleremia,commonly known as "rabbit fever" can be communicated across several species including rabbits, rodents and humans. Developed by Jorge L.Benach, PH.D., director of the Center for Infectious Diseases in the Center for Molecular Medicine, and chair of the Department of Molecular Genetics and Microbiolgy at Stony Brook University.
This murine IgG monoclonal antibody recognizes a native epitope of Francisella tularensis "Live Vaccine Strain"; monoclonal antibody clone 163 against a native epitope of Francisella tularensis protein bacterioferritin.
The antibody was developed from a mouse infected with F.tularensis live vaccine strain and not recombinant protein, therefore representing a natural antibody made by the mouse in defense of infection against a native epitope of tularensis protein.
Stony Brook University is actively seeking companies interested in licensing a Francisella tularensis infection- derived monoclonal antibody for use in detecting infectious diseases and bioterrorism.
Available for License
Monoclonal antibody, F. tularensis LVS, bacterioferritin
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