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Rationally Designed Aromatase Inhibitors as Anti-Breast Cancer Agents

We have developed exemestane-based vinyl diazo compounds that act as aromatase inhibitors to be used in the treatment of cancer, particularly breast and ovarian cancer. Exemestane is structurally related to androstenedione and acts as an irreversible, steroidal aromatase inactivator. Our aromatase inhibitors are based upon the steroid scaffold...
Published: 12/18/2017   |   Inventor(s): Debashis Ghosh
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Category(s): Technology Classifications > Healthcare, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines

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