Rationally Designed Aromatase Inhibitors as Anti-Breast Cancer Agents
have developed exemestane-based vinyl diazo compounds that act as aromatase
inhibitors to be used in the treatment of cancer, particularly breast and
ovarian cancer. Exemestane is structurally related to androstenedione and acts
as an irreversible, steroidal aromatase inactivator. Our aromatase inhibitors
are based upon the steroid scaffold...
Inventor(s): Debashis Ghosh
Category(s): Technology Classifications > Healthcare, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines