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for "diagnostics"
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Development of a Pediatric Tuberculosis Diagnostic Test

A lipoprotein diagnostic marker for TB disease ideal for a simple diagnostic assay from a finger prick blood or serum Background: The inadequate sensitivity of available organism-based TB diagnostic tools in children, the wide spectrum of disease observed in children, and the non-specific signs and symptoms especially in young and HIV-children, contribute...
Published: 8/28/2020   |   Inventor(s): Nicole Sampson, Xinxin Yang
Keywords(s): antibody, biomarker, diagnosis, ELISA, modified LDL, Technologies, tuberculosis
Category(s): Antibodies, Diagnostics, Campus > Stony Brook University

Novel EGFR Truncations as Biomarker and Target

Three mutations that could be used as biomarkers for patient's drug responses or for tumor therapeutic targets Background: Three new truncation mutants have been discovered in primary human tumors and cell lines. These mutants may possess oncogenic activities and render some tumors resistant to certain inhibitors. These newly discovered mutants may...
Published: 8/27/2020   |   Inventor(s): Edward Chan, James Keller
Keywords(s): EGFR471, EGFR660, EGFR768, Technologies, truncated EGFR
Category(s): Diagnostics, Campus > Stony Brook University

Extraction of Respiratory Rate from Pulse Oximeter Recordings

An algorithm that uses pulse oximeter signals to estimate a respiratory rate with more accurate results and time-frequency resolution Background: Pulse oximeters are simple, non-invasive instruments used extensively in hospitals and emergency rooms to acquire patient oxygen saturation and cardiac functions. To maximize the potential of pulse oximetry,...
Published: 8/27/2020   |   Inventor(s): Ki Chon, Kihwan Ju
Keywords(s): pulse oximeter, respiration rate, Technologies
Category(s): Diagnostics, Medical Devices, Campus > Stony Brook University

Using Algorithms to Identify Fractures in Digitized X-rays

Combination of algorithms that use local geometry, edge detection, and advanced image processing to recognize fractures in digital x-rays Background: One of the most common reasons people go to any medical office is due to musculoskeletal injuries. Regardless of where patients go (primary physician's office, orthopedic surgeon's office, emergency...
Published: 7/7/2020   |   Inventor(s): Fazel Khan, Imin Kao, Sajid Khan, Jafar (1) Khan, P.E.
Category(s): Computer Software, Diagnostics, Healthcare IT, Medical Imaging, Campus > Stony Brook University

Scintillating Substrate Compositions and Coatings for Dual-Screen Flat-Panel Detector Improvements

Using light-scattering glass-ceramic scintillators to increase the sensitivity and detective quantum efficiency of flat-panel detectors Background: There is a need for improvements in diagnostic imaging devices that are utilized in various clinical applications. Two notable clinical applications where detectors have a relatively poor performance are...
Published: 7/7/2020   |   Inventor(s): Anthony Lubinsky, Adrian Howansky
Category(s): Dental, Diagnostics, Medical Devices, Medical Imaging, Nanotechnology, Optics and Photonics, Sensors, Campus > Stony Brook University

System, Method, and Computer-Accessible Medium for Virtual Pancreatography

A novel process for virtual pancreatography using computer-aided diagnosis ("CAD") Background: Pancreatic cancer is potentially one of the most fatal cancers; it has an overall five-year survival rate of less than 9%. This is due to poor prognosis, and because it has no specific early symptoms. However, detecting precursors of pancreatic...
Published: 7/6/2020   |   Inventor(s): Arie Kaufman, Konstantin Dmitriev
Category(s): Computer Software, Diagnostics, Healthcare IT, Medical Devices, Medical Imaging, Campus > Stony Brook University

System, Method and Computer-Accessible Medium for Ultralow Dose Computed Tomography Image Reconstruction

Use of systems to create a higher quality, more accurate image Background: Computer tomography (CT) currently operates at high X-ray exposure, in terms of high X-ray flux. These images provide key details into warning such as potential lung cancer in smoking patients, or even possible birth defects in children. However, there are still challenges...
Published: 7/6/2020   |   Inventor(s): Zhengrong Liang, Yuxiang Xing, Hongbing Lu, Yongfeng Gao
Category(s): Computer Software, Diagnostics, Healthcare IT, Medical Imaging, Campus > Stony Brook University

Dual-screen Digital Radiography with Asymmetric Reflective Screens

This novel radiography technology uses dual screens to project a clearer image of an object. Background: In digital radiography, an imaging system may include a screen that absorbs radiation and produces light, where the produced light is sensed by an array of photosensors to generate electrical signals. The generated electrical signals may be used...
Published: 7/6/2020   |   Inventor(s): Anthony Lubinsky, Wei Zhao
Keywords(s): Technologies
Category(s): Diagnostics, Medical Devices, Campus > Stony Brook University

Noninvasive Epithelial Cancer Diagnosis and Grading

A novel OCT system to acquire high resolution, in-depth optical images of living tissue samples. Background: Optical Coherence Tomography (OCT) works by projecting a laser into tissue. When the light is reflected back, the OCT microscope uses an optical interferometer to detect a proportion of the light that is least back scattered. The system...
Published: 7/5/2020   |   Inventor(s): Yingtian Pan
Category(s): Diagnostics, Medical Imaging, Campus > Stony Brook University

Novel Monoclonal Antibodies to Treat Carbapenem-resistant Klebsiella pneumoniae Infections

These mABs elicit phagocytic activity and protective immune response to clear bacteria from infected mice. Background: Carbapenem-resistant K.pneumonia (CR-Kp) strains are a major threat worldwide due to the difficult to treat. Lack of new antibiotics in pipeline and the emergence of resistance to the last-resource antibiotics has resulted in...
Published: 1/24/2020   |   Inventor(s): Bettina Fries, Elizabet Diago Navarro
Keywords(s): Technologies
Category(s): Antibodies, Diagnostics, Therapeutics, Campus > Stony Brook University
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