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mAbs Inhibit Human RAGE by Blocking Its Binding to Heparan Sulfate

Monoclonal antibodies that block heparan sulfate binding to human RAGE, preventing its activation in disease states to serve as a therapeutic treatment. Background: Receptor for Advanced Glycation End products (RAGE), a widely expressed inflammatory receptor for disease states such as atherosclerosis, cancer, Alzheimer disease, drug-induced liver...
Published: 3/8/2024   |   Inventor(s): Ding Xu, Chih Yean Ong, Miaomiao Li
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Antibodies, Technology Classifications > Therapeutics and Vaccines

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