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Novel three-dimensional, conformal microelectrode arrays for interrogating and manipulating three-dimensional cell culture systems

A flexible, biocompatible microelectrode array wraps around 3D cell cultures such as organoids, enabling comprehensive electrical recording and stimulation for advanced research, drug testing, and personalized medicine, overcoming the limitations of traditional flat electrode arrays. Background: Three-dimensional (3D) cell culture systems, such as...
Published: 2/18/2026   |   Inventor(s): Susan Sharfstein, Nathaniel Cady, Yubing Xie, Natalya Tokranova, Anthony Manning, Fernando Pesantez Torres
Keywords(s): 3D culture, 3D flexible microelectrode, electrophysiology, microelectrode array, microfabrication, neurodegeneration, organoid, polymer materials, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering

Novel Cryoelectrospun Scaffolds for Tissue Engineering and Methods for Manufacturing

Methods to produce 3D nanofibrous scaffolds that closely mimic soft-tissue stromal ECM using a unique cryoelectrospinning process. Background: The extracellular matrix (ECM) comprising the proteinaceous scaffold within the connective tissue is involved in regulating the function of parenchymal tissue in organs. When that becomes stiff, or fibrotic,...
Published: 1/30/2026   |   Inventor(s): Susan Sharfstein, Yubing Xie, Pujhitha Ramesh, James Castracane, Melinda Larsen
Keywords(s): Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Screens and Assays, Campus > University at Albany

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