Affinity Purified, Polyclonal Anti-Erlin1 Antibody
Antibody against Endoplasmic reticulum lipid raft associated 1 (Erlin-1; also known as anti-KE04 and anti-SPFH)
Erlin1 (endoplasmic reticulum lipid raft associated 1) is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. https://www.ncbi.nlm.nih.gov/gene/10613
- Polyclonal, affinity-purified
- Immunogen: amino acids 332-346 of rat Erlin-1
- Western blot
- ELISA
- Immunoprecipitation
- Immunofluorescence assays
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