Affinity Purified, Polyclonal Anti-Erlin2 Antibody

Anit-erlin2 is an affinity purified rabbit polyclonal antibody raised against amino acids 321-339 of rat erlin2; DKLGFGLEDEPLETATKDN). Erlin2 is a recently-characterized endoplasmic reticulum (ER) membrane protein that that forms a complex with erlin1 and has a putative role in the cellular process known as endoplasmic reticulum-associated degradation.  Its official name is endoplasmic reticulum lipid raft-associated protein 2. It has also been referred to as NET32, SPFH2 (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2), SPG18, C8orf2, and Erlin-2. It recognizes erlin2 (43kDa) in all mammalian species tested (human, rat and mouse) in immunoblots, immunoprecipitation and in immunofluorescence microscopy. Raising and use of Anti-erlin2 are described in: Pearce, M.M., Wang, Y., Kelley, G.G. and Wojcikiewicz, R.J.H. (2007) SPFH2 mediates the ERAD of IP3 receptors and other substrates in mammalian cells. J. Biol. Chem. 282, 20104-20115.

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