Raman Spectroscopy for Testing Stability of RNA-based Vaccines and Drugs
A fast, less expensive, and more reliable method for assessing mRNA degradation in vaccines, that can also be used as a tool for the development of new RNA-based therapeutics.
Background:
The development of mRNA-based vaccines for COVID-19 offers the potential for a new medical paradigm based on RNA technology. Unfortunately, these drugs require...
Published: 4/1/2025
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Inventor(s): Igor Lednev, Alexander Shekhtman, Lamyaa Almehmadi, Sergei Reverdatto
Keywords(s): drug stability, mRNA, mRNA stability, Raman spectroscopy, RNA, Technologies, vaccine stability, vaccines
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors
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Algorithm for Identifying Images of Fluorescently-Labeled Cells
Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more.
Background:
Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...
Published: 4/1/2025
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Inventor(s): Alex Valm, Yunlong Feng
Keywords(s): bacterial cells, bacterial infection, bioengineering, biofilm control, bioinformatics, biomarker diagnostics, biomarkers, cancer, cell biology, computational biology, dental, diagnostics, digital image processing, fluorescence, fluorescence spectroscopy, gene expression analysis, image analysis, image processing, machine learning, medical imaging, microbial pathogenesis, personalized medicine, RNA, saliva, scanning microscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors
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IgA Monoclonal Antibodies as a Prophylactic and Therapeutic Treatment for Dengue Virus Infection
Enables the prevention and treatment of dengue by avoiding the challenge of Antibody Dependent Enhancement. Background: Dengue virus is one of the most widespread vector-borne viral pathogens in the world. Nearly 400 million dengue virus infections occur each year, resulting in approximately 20,000 deaths. In addition, dengue-associated illness comprises...
Published: 4/1/2025
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Inventor(s): Adam Waickman, Adam Wegman
Keywords(s): antibody, antibody therapy, biologics, biomedical, disease prevention, immunotherapy, monoclonal antibody, Technologies, viral immunology, viral pathogenesis
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Antibodies, Technology Classifications > Healthcare, Technology Classifications > Viral Vectors, Campus > Upstate Medical University
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Codagenix, Inc.
https://codagenix.com/
https://codagenix.com/
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Published: 4/1/2025
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Inventor(s): Stony Brook University
Keywords(s): Startups
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Viral Vectors, Campus > Stony Brook University
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Blocking Covid-19 Virus from Entering the Nares, Nasolaryngeal and Pulmonary Airways Using Ace2 Peptides
Prevents initial COVID-19 infection and neutralizes COVID-19 in an existing pulmonary infection.
Background:
COVID-19 remains one of the primary global health issues facing society today. The economic and social impact of the virus will likely be significant for the foreseeable future. Although effective vaccines have been developed, COVID-19 infection...
Published: 4/1/2025
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Inventor(s): Matthew Pincus
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors
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