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Alternative to Antibody Drug Conjugates

Antibody Drug Complexes (ADCx) that serve as potentially safer alternatives to traditional Antibody Drug Conjugates (ADCs). Background: While ADCs have seen some success in the market, toxicity issues have limited the class from reaching its full potential. Toxicity of these agents stems from exposure of their payloads (e.g. auristatin), primarily...
Published: 3/8/2024   |   Inventor(s): Brandon Bordeau, Joseph Balthasar
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Antibodies, Technology Classifications > Drug Delivery

Abcombi Biosciences, Inc.

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Published: 2/13/2024   |   Inventor(s): University at Buffalo
Keywords(s): Startups
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Delivery, Campus > University at Buffalo

Codagenix, Inc.

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Published: 3/12/2024   |   Inventor(s): Stony Brook University
Keywords(s): Startups
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Viral Vectors, Campus > Stony Brook University

CH3 Biosystems, LLC

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Published: 2/13/2024   |   Inventor(s): University at Buffalo
Keywords(s): Startups
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Biomedical Science and Engineering, Campus > University at Buffalo

Tonus Therapeutics

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Published: 3/11/2024   |   Inventor(s): University at Buffalo
Keywords(s): Startups
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Campus > University at Buffalo

Daedalus Innovations, LLC

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Published: 3/12/2024   |   Inventor(s): University at Buffalo
Keywords(s): Startups
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Bioinformatics, Campus > University at Buffalo

PeptiDream, Inc.

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Published: 3/11/2024   |   Inventor(s): University at Buffalo
Keywords(s): Startups
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Campus > University at Buffalo

A Supramolecular Chitosan Complex Drug Delivery Platform

Using a supramolecular chitosan complex system to bind hydrophobic substances including small spherical molecules and/or linear chainsRSS.HDBackground> Background: <Since 1991, copolymers that form well-defined micelles in aqueous media have been studied and research has shown that these copolymers can trap water‑insoluble substances in their...
Published: 2/1/2024   |   Inventor(s): Yizhi Meng
Keywords(s): Technologies
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Material and Composites, Campus > Stony Brook University

Nucleic Acids that Encode Sodium Channels

Provides a method for screening compounds for use as anti-arrhythmic agents and other medications using mutant mammalian voltage-gated sodium channel subunit. Background: Mammalian voltage-gated sodium channels are pore-forming membrane proteins responsible for the initiation and propagation of actions in nerve, skeletal muscle, and heart cells. The...
Published: 1/29/2024   |   Inventor(s): Sho-Ya Wang
Keywords(s):  
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Technology Classifications > Drug Delivery

Laser Ablation Direct Analysis in Real Time-Imaging Mass Spectrometry (LADI-MS)

Offers the potential of real-time small-sample analysis for a very large variety of applications. Background: Real Time Imaging Mass Spectrometry (RTMS) is a method for analyzing and identifying biological samples in real time. RTMS can be used in an extremely broad variety of applications, involving chemistry, biochemistry, food sciences, and medicine....
Published: 1/23/2024   |   Inventor(s): Rabi Musah
Keywords(s): analytical chemistry, Biomarker discovery, chemistry, forensic testing, image acquisition, imaging, life sciences, Mass spectrometry imaging, medical imaging, Natural products, Phytochemistry, Small-molecule profiling, Small-molecule spatial distribution mapping, Species discrimination, Species identification, Technologies, Tissue analysis, wood anatomy, wood science
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Environment, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents
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