A Novel Marker for Detection of Prostate Cancer

Myosine IC isoform A is overexpressed in prostate cancer tissues and metastatic cells.  The monoclonal antibodies and PCR tools developed here detect overexpression.

In 2012 a novel isoform of myosine IC designated isoform A was discovered.  Several years later tissue distribution studies discovered it was overexpressed in prostate cancer tissues and metastatic cells.  Overexpression of isoform A can be detected at both the protein and RNA level.  The tools developed by the inventors for expression detection include monoclonal antibodies and PCR. 

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