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A HNF4a-caGR fusion transcription factor as potential treatment for inflammatory liver diseases and liver cancer

The HNF4α-caGR fusion transcription factor is an innovative therapeutic protein designed to restore liver function and reduce inflammation in liver diseases and liver cancer by simultaneously activating key regulatory pathways. Background: Liver diseases and liver cancer often involve impaired function of hepatocyte nuclear factor 4α...
Published: 8/27/2026   |   Inventor(s): Hong Lu
Keywords(s): anticancer therapeutic, anti-inflammatory therapeutic, gene therapy, liver disease, sepsis, Technologies, tumor suppressor genes
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines

Regulatory BC200 RNA in Beast Cancer

This technology is a novel breast cancer treatment that uses small interfering RNAs to silence BC200 RNA. Background: Breast cancer incidence rates have been slowly but steadily increasing over the last two decades. Despite improvements in early detection methods and therapeutic interventions, breast cancer remains a leading cause of cancer death...
Published: 4/7/2026   |   Inventor(s): Valerio Berardi, Henri Tiedge
Keywords(s): anticancer therapeutic, biomedical science, regulatory RNAs, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Therapeutics and Vaccines

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