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Device and Methods for Telehealth Wound Care

An inexpensive, hand-held optical device capable of imaging wounds for telehealth monitoring of healing and vascular structure. Background: Open sores and wound healing are a pressing concern in medical care of limited mobility patients. For instance, diabetic foot ulcers are associated with a 25% 5 year mortality rate as well as other complications....
Published: 11/21/2024   |   Inventor(s): Wenyao Xu, Jun Xia, Alexander Gherardi, Tianyu Chen
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging

Development of Lectins with Protein Engineering

Lectins that exclusively bind sialylated core-2 O-linked glycans within cancerous tissue with a higher affinity than physiologically healthy tissue. Background: Lectins bind complex carbohydrates on cell surfaces and secreted glycoproteins. These carbohydrates are modified during disease from altered metabolism, though the proteins themselves are...
Published: 11/20/2024   |   Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays

Method for Minimizing Coaxial Cable Effects on Measurements in Electrical Impedance Tomography

This technology compensates for the effects of a cable connecting a source to a load during electrical impedance tomography measurements. Background: In electrical impedance tomography, multiple current sources are connected via cables to electrodes on the body surface. These current sources apply precise current patterns to the body. Applied currents...
Published: 11/15/2024   |   Inventor(s): Gary Saulnier, Omid Rajabi Shishvan, Ahmed Abdelwahab
Keywords(s): cable compensation, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Energy, Technology Classifications > Energy Conservation, Technology Classifications > Engineering

Determining Bloodstain Age Using Raman Spectroscopy

A novel and non-destructive method of determining the age of an evidentiary bloodstain using Raman Spectroscopy. Background: Forensic investigators are members of law enforcement that help secure a crime scene and collect evidence. When the evidence involves blood, the age of that blood is a critical piece of information investigators need to identify...
Published: 11/1/2024   |   Inventor(s): Igor Lednev
Keywords(s): TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering

Three-Point Bending Cylinder (3PBC) Test System

This technology is a new asphalt mixture fatigue testing system that is practical, fast, and cost-effective. Background: According to a recent survey of state Departments of Transportation, many agencies consider fatigue cracking the most common type of asphalt failure that needs to be addressed. The same survey also indicated that a fatigue cracking...
Published: 10/25/2024   |   Inventor(s): Aksel Seitllari
Keywords(s): asphalt fatigue cracking, Technologies, Three-Point Bending Cylinder Test, Timoshenko Beam Theory, ViscoElastic Continuum Damage
Category(s): Campus > SUNY Canton

RNA-aptamer-mediated Bacteriophage Purification

A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 10/3/2024   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

Raman Spectroscopy for Testing Stability of RNA-based Vaccines and Drugs

A fast, less expensive, and more reliable method for assessing mRNA degradation in vaccines, that can also be used as a tool for the development of new RNA-based therapeutics. Background: The development of mRNA-based vaccines for COVID-19 offers the potential for a new medical paradigm based on RNA technology. Unfortunately, these drugs require...
Published: 10/3/2024   |   Inventor(s): Igor Lednev, Alexander Shekhtman, Lamyaa Almehmadi, Sergei Reverdatto
Keywords(s): drug stability, mRNA, mRNA stability, Raman spectroscopy, RNA, Technologies, vaccine stability, vaccines
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors

Secure Multi-Source Key Dissemination Using Network Coding

A secure key-cast network design to ensure positive-rate key dissemination while preventing non-terminal nodes from accessing information. Background: In cryptographic applications, disseminating a secret key among network nodes while ensuring that non-terminal nodes do not gain any information about the key is a critical challenge. This concept,...
Published: 11/12/2024   |   Inventor(s): Michael Langberg, Michelle Effros
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Computers, Technology Classifications > Information Technology

Suppression of Therapeutic Escape in Breast Cancer by BTK Inhibition

This technology offers the potential of new and novel cancer treatments based on various inhibitors of protein tyrosine kinases Background: Genes that regulate extracellular growth, differentiation, and developmental signals are commonly mutated in cancers. Protein tyrosine kinases (PTKs) mediate the reversible process of tyrosine phosphorylation,...
Published: 9/5/2024   |   Inventor(s): Douglas Conklin, Xianhui Wang
Keywords(s): breast cancer, cancer, Technologies, therapeutic targets
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Therapeutics and Vaccines

In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses

This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases. Background: In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...
Published: 10/3/2024   |   Inventor(s): Alex Valm
Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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