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Chip-scale Photonic Processing Neuroprosthetic Detector

A novel technology for optimizing visual prosthetics for individuals with foveal blindness. Background: The International Agency for the Prevention of Blindness expects 196 million people to suffer from macular degeneration worldwide in 2020. Millions more will suffer from traumatic ocular injury or glaucoma or other foveal defects. The result will...
Published: 9/13/2024   |   Inventor(s): Stephen Macknik, Susana Martinez-Conde, Satyavolu Papa Rao, Spyridon Galis, John Carter, Olivya Caballero
Keywords(s): brain, cortex, multi-color spatiochromatic encoding, neural recording, OBServ, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare, Technology Classifications > Medical Devices, Campus > NY CREATES, Campus > SUNY Polytechnic Institute

Chromatic Bioluminescence as a Cellular Level Readout System of Neural Activity

This technique could be used to visualize neuronal activity in the brain, in nerves, or in ex vivo systems. Background: Some compounds can emit luminescence in response to changes in intracellular ion concentrations. Neuronal depolarization, and the generation of an action potential, involves an elevation in intracellular calcium, which causes the...
Published: 7/11/2023   |   Inventor(s): Stephen Macknik, Susana Martinez-Conde
Keywords(s): bioluminescence, optogenetic brain system, prosthetic vision, restoration of vision, Technologies, visual cortex
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Biomedical Science and Engineering

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