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6-Mer Peptide for Anti-Cancer Therapeutic Use

A 6-mer peptide (Win6mer) has been designed which has potential as an anti-cancer therapeutic. The Win6mer disrupts MLL1 and SETd1A core complex assembly, but does not inhibit isolated SET domain activity. MLL I belongs to the SETI family of histone H3 lysine 4 (H3K4) methyltransferases, comprised of MLLl-4 and SETdlA/B. MLLl translocations are present...
Published: 6/22/2020   |   Inventor(s): Michael Cosgrove, Nilda Alicea-Velazquez, Stephen Shinsky
Keywords(s): #SUNYresearch, Technology
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University

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