Enzymatic Pyruvate Depletion as Adjunctive Therapy for the Treatment of Biofilm-Related Infections
This technology utilizes a new approach to modulating the extracellular metabolites of biofilm cells to enhance the ability of antimicrobial agents and/or the immune system to control the growth and persistence of microorganisms in medical settings and aqueous systems.
- Approach capable of targeting resistant biofilm cells.
- Mechanism of action and experimental data suggest very low likelihood of the emergence of resistance.
- Can be used synergistically with other antimicrobials and dispersion-inducing compounds.
Binghamton University RB567