Self-Powered Paper Patch for Glucose Monitoring in Sweat

Regular physical exercise provides effective diabetes management, decreases risk of cardiovascular disease, and improves body composition. However, such physical exertion can increase the risk of hypoglycemia in insulin-dependent diabetes mellitus, causing irritability, confusion, and even seizures and unconsciousness. Today’s most widespread methods for glucose self-testing involves monitoring the blood glucose levels. Such techniques use a lancet device to manually prick the skin for the blood sample. Then, the sample is positioned onto a disposable test strip, which is inserted into a portable glucometer to read an electrochemical signal and calculate the blood glucose levels. However, the conventional measurements are not suitable for preventing hypoglycemia during exercise. The present invention provides a paper-based self-powered sensor patch for glucose monitoring in sweat and for the prevention and management of exercise-induced hypoglycemia. The technology demonstrates the sensing concept for self-powered, wearable, and disposable glucose monitoring in sweat. The fuel cell-based sensor is composed of three functional layers: (1) the anodic layer with a conductive reservoir, (2) the sweat reservoir, and (3) the air-cathode layer. When attached directly to human skin, sweat is wicked by using capillary forces and monitored an electrochemical current generation as a transducing output signal for glucose monitoring in sweat. Thus, it eliminates the requirement of exterior batteries and advances readout instrumentation.

Advantages:

  • Non-invasive.
  • Disposable.
  • Equipment-free.
  • Portable.
  • Low-cost.

 

Binghamton University RB547

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