Fast, Background-free Detection of Nucleic Acid Sequences Using DNA Nanoswitches
This technology introduces DNA-based "nanoswitches"—innovative nanostructures that enable precise and efficient detection of target analytes through conformational changes.
Background:
Accurate detection of specific molecules, such as DNA sequences or other analytes, is fundamental in medical diagnostics, environmental monitoring, and biochemical...
Published: 5/6/2026
|
Inventor(s): Kenneth Halvorsen, Wesley Wong, Arun Richard Chandrasekaran
Keywords(s):
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
|
Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications.
Background:
Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/26/2026
|
Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): aptamers, DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
|
Ribonuclease-responsive DNA Nanoswitches
A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample.
Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 1/30/2026
|
Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics
|