Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care
A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background:
Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 5/13/2025
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Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines
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Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity
An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva.
Background:
Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 5/13/2025
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Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium
Produces cyclic peptide libraries quickly, cheaply, and without the need of purification.
Background:
Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 5/13/2025
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Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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Data Compression and Encryption for Multimedia
A data compression and encryption technology to enhance the quality and security of multimedia access.
Background:
With mobile high-speed networks evolving from 5G to 6G and the advent of edge and quantum computing, coupled with the explosive growth of social media and downloadable entertainment, large-file (high-resolution) multimedia consumption...
Published: 5/13/2025
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Inventor(s): Ziya Arnavut, Basar Koc, Hüseyin Koçak
Keywords(s): audio, data compression, encryption, imaging, medical imaging, multimedia, Technologies
Category(s): Campus > SUNY Fredonia, Technology Classifications > Computers, Technology Classifications, Technology Classifications > Information Technology, Technology Classifications > Data
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Ribonuclease-responsive DNA Nanoswitches
A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample.
Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 5/13/2025
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Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics
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Inhibition of ITK by Novel SLP76pTYR Targeted Only ITK Signaling and Enhanced Tregs
Facilitates graft-versus-leukemia effect (GVL) while minimizing graft-versus-host disease (GVHD).
Background:
Graft versus host disease (GVHD) remains the second leading cause of death following allogeneic hematopoietic stem cell transplant (allo-HCT). In allo-HCT, mature donor T cells in the donor inoculum play a central role in mediating...
Published: 5/13/2025
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Inventor(s): Mobin Karimi, Alaji Bah
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Healthcare
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Targeting the Folding of Hsp90 Clients by Predicting Their Local Unfolding Status
Computationally predicts potential ideal interaction points for the molecular chaperone heat shock protein-90 (Hsp90).
Background:
Molecular chaperones assist in the folding of unfolded and misfolded polypeptides by stabilization of folding intermediates and prevention of protein misfolding and aggregation. Molecular chaperones are present in all...
Published: 5/13/2025
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Inventor(s): Mehdi Mollapour, Giorgio Colombo, Mark Woodford, Gennady Bratslavsky, Dimitra Bourboulia
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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New Liquid Cooling System for High Power Electronics Package
Provides direct cooling for data centers, microelectronics packages, and chips via a fluid cooling system. Background: During operation, high-power electronics typically generate high heat. To avoid degradation and fault within the electronics, this heat must be continuously removed. Air cooling is one traditional method of dissipating this heat....
Published: 5/13/2025
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Inventor(s): Leila Choobineh, Bahgat Sammakia
Keywords(s):
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications, Technology Classifications > Electronics, Campus > Binghamton University
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Response-Based Optimization of Multichannel Microstimulation for Somatosensory Neural Prostheses
A novel tool for developing protheses for restoring motor and sensory function for limb loss and spinal cord patients. Background: Somatosensory prostheses are being developed as part of the research into motor-brain-machine interfaces. These technologies offer new possibilities for restoring motor and sensory function for patients who have suffered...
Published: 5/13/2025
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Inventor(s): John Choi, Joseph Francis, Austin Brockmeier, Jose Principe
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Healthcare, Campus > SUNY Downstate Health Sciences University
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Whole Blood Transcript Clusters for Ischemic Stroke Detection
Provides a better method for diagnosing acute ischemic stroke. Background: Strokes result from reductions of blood flow to the brain and are second to coronary heart disease in terms of vascular disease incidence, morbidity, and mortality. About 83% of strokes are due to arterial vascular occlusion (ischemic stroke), and about 17% are due to vascular...
Published: 5/13/2025
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Inventor(s): Alison Baird, Mateusz Adamski, Steven Soper, Malgorzata Witek
Keywords(s):
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications, Technology Classifications > Research Tools and Reagents
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