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Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity

An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva. Background: Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 4/1/2025   |   Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines

Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium

Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 4/1/2025   |   Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

Data Compression and Encryption for Multimedia

A data compression and encryption technology to enhance the quality and security of multimedia access. Background: With mobile high-speed networks evolving from 5G to 6G and the advent of edge and quantum computing, coupled with the explosive growth of social media and downloadable entertainment, large-file (high-resolution) multimedia consumption...
Published: 4/1/2025   |   Inventor(s): Ziya Arnavut
Keywords(s): audio, data compression, encryption, imaging, medical imaging, multimedia, Technologies
Category(s): Campus > SUNY Fredonia, Technology Classifications > Computers, Technology Classifications > Medical Imaging, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare IT, Technology Classifications > Information Technology, Technology Classifications > Research Tools and Reagents

Ribonuclease-responsive DNA Nanoswitches

A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample. Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 4/1/2025   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics

Targeting the Folding of Hsp90 Clients by Predicting Their Local Unfolding Status

Computationally predicts potential ideal interaction points for the molecular chaperone heat shock protein-90 (Hsp90). Background: Molecular chaperones assist in the folding of unfolded and misfolded polypeptides by stabilization of folding intermediates and prevention of protein misfolding and aggregation. Molecular chaperones are present in all...
Published: 4/1/2025   |   Inventor(s): Mehdi Mollapour, Mark Woodford, Gennady Bratslavsky, Dimitra Bourboulia
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines

New Liquid Cooling System for High Power Electronics Package

Provides direct cooling for data centers, microelectronics packages, and chips via a fluid cooling system. Background: During operation, high-power electronics typically generate high heat. To avoid degradation and fault within the electronics, this heat must be continuously removed. Air cooling is one traditional method of dissipating this heat....
Published: 4/1/2025   |   Inventor(s): Leila Choobineh, Bahgat Sammakia
Keywords(s):  
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications, Technology Classifications > Electronics, Campus > Binghamton University

6-azasteroids with unique activity in mycobacteria

The compound functions as potentiators of several anti-tuberculosis drugs RSS.HDBackground> Background: < One third of the world’s population is infected with tuberculosis (TB). In 2014, there were 1.5 million TB related deaths. There are drugs to combat the bacteria by attacking the bacteria directly. The current recommended treatment...
Published: 2/4/2025   |   Inventor(s): Nicole Sampson, Joshua Werman, Tianao Yuan
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Drug Design and/or Synthesis, Campus > Stony Brook University

Laser Assisted Ignition Method to Enable Ammonia Combustion

Overcoming carbon-free fuel challenges: laser-induced Ammonia combustion RSS.HDBackground> Background: < Decarbonization of the power production, transportation, industrial and building heating sectors is pivotal for meeting net-zero carbon goals of 2050. As solar and wind are rapidly brought online to decarbonize the power grid, we are faced...
Published: 1/29/2025   |   Inventor(s): Dimitris Assanis, David Hwang
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Clean Energy, Technology Classifications > Environment, Technology Classifications > Energy Conservation, Campus > Stony Brook University

Self-Sustained Hydrogen Production

A self-sustained compact reactor for continuous hydrogen gas production from ammonia decomposition.­ Background: Hydrogen offers advantages as a clean and safe fuel for broad applications, but its storage and transport are expensive. Conversely, ammonia is an effective hydrogen carrier, as it contains 17.6% hydrogen by weight and can be economically...
Published: 1/28/2025   |   Inventor(s): Amr Ibrahim, Miao Yu, Sung Hwan Park, Saman Emami Gerami
Keywords(s): Chemistry, Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications, Technology Classifications > Energy, Technology Classifications > Engineering, Technology Classifications > Instrumentation, Technology Classifications > Materials and Chemicals

Creep Resistant Cu-based CuCrNbZr Alloy with High Thermal Conductivity

A novel Cu-based alloy with high thermal conductivity and thermal creep resistance for high-temperature applicationsRSS.HDBackground> Background: <High strength, high conductivity copper (Cu) alloys are a potentially attractive option for a variety of demanding high heat flux structural applications ranging from aerospace to fusion energy. Fusion...
Published: 4/26/2024   |   Inventor(s): Lance Snead, Lizhen Tan, Ling Wang, Steven Zinkle
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Material and Composites, Campus > Stony Brook University
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