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Akai Kaeru, LLC

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Published: 3/11/2024   |   Inventor(s): Stony Brook University
Keywords(s): Featured, Startups
Category(s): Campus > Stony Brook University, Technology Classifications, Technology Classifications > Artificial Intelligence

Creep Resistant Cu-based CuCrNbZr Alloy with High Thermal Conductivity

A novel Cu-based alloy with high thermal conductivity and thermal creep resistance for high-temperature applicationsRSS.HDBackground> Background: <High strength, high conductivity copper (Cu) alloys are a potentially attractive option for a variety of demanding high heat flux structural applications ranging from aerospace to fusion energy. Fusion...
Published: 2/1/2024   |   Inventor(s): Lance Snead, Lizhen Tan, Ling Wang, Steven Zinkle
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Material and Composites, Campus > Stony Brook University

Production of Salivary Gland Epithelial Progenitors and Acinar Organoids

Human UPSC-based tissue engineering system to develop salivary gland epithelial progenitors used to construct acinar organoids that mimic glandular microarchitecture and function. Background: Organoids are three-dimensional cell constructs that replicate the complicated tissue microarchitecture of specialized epithelial tissues. These constructs...
Published: 3/8/2024   |   Inventor(s): Stelios Andreadis, Ronel Samuel, Olga Baker, Kihoon Nam
Keywords(s): Biomedical Engineering, Biotechnology, Featured, Medical Devices, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Screens and Assays

Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium

Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 1/18/2024   |   Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care

A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background: Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 4/3/2024   |   Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines

Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity

An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva. Background: Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 4/3/2024   |   Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines

Data Compression and Encryption for Multimedia

A data compression and encryption technology to enhance the quality and security of multimedia access. Background: With mobile high-speed networks evolving from 5G to 6G and the advent of edge and quantum computing, coupled with the explosive growth of social media and downloadable entertainment, large-file (high-resolution) multimedia consumption...
Published: 1/12/2024   |   Inventor(s): Ziya Arnavut
Keywords(s): audio, data compression, encryption, imaging, medical imaging, multimedia, Technologies
Category(s): Campus > SUNY Fredonia, Technology Classifications > Computers, Technology Classifications > Medical Imaging, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare IT, Technology Classifications > Information Technology, Technology Classifications > Research Tools and Reagents

Ribonuclease-responsive DNA Nanoswitches

A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample. Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 1/22/2024   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics

Inhibition of ITK by Novel SLP76pTYR Targeted Only ITK Signaling and Enhanced Tregs

­Facilitates graft-versus-leukemia effect (GVL) while minimizing graft-versus-host disease (GVHD). Background: Graft versus host disease (GVHD) remains the second leading cause of death following allogeneic hematopoietic stem cell transplant (allo-HCT). In allo-HCT, mature donor T cells in the donor inoculum play a central role in mediating...
Published: 7/11/2023   |   Inventor(s): Mobin Karimi, Alaji Bah
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Healthcare

Targeting the Folding of Hsp90 Clients by Predicting Their Local Unfolding Status

Computationally predicts potential ideal interaction points for the molecular chaperone heat shock protein-90 (Hsp90). Background: Molecular chaperones assist in the folding of unfolded and misfolded polypeptides by stabilization of folding intermediates and prevention of protein misfolding and aggregation. Molecular chaperones are present in all...
Published: 7/11/2023   |   Inventor(s): Mehdi Mollapour, Mark Woodford, Gennady Bratslavsky, Dimitra Bourboulia
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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