Portable Assay for COVID-19 Diagnostic
A low-cost, rapid, and more accurate gel electrophoresis-based assay using DNA nanoswitches for detecting COVID-19 and other viruses.
Background:
Viral diagnostics are of prime importance for testing infection rates and for timely treatment, especially in the case of a pandemic such as the current COVID-19 outbreak caused by the SARS-CoV-2 corona...
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen, Lifeng Zhou
Keywords(s): DNA, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Ribonuclease-responsive DNA Nanoswitches
A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample.
Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics
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RNA Purification with DNA Nanoswitches
Novel, user-centric technology for detecting and analyzing RNA that accelerates the pace of discovery in RNA research. Background: RNA purification is an important part of biomedical research, and very few tools exist for pulling specific RNAs out of a complex solution. Further, understanding of RNA and its complex roles in biology is constantly evolving....
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen, Lifeng Zhou
Keywords(s):
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Research Tools and Reagents
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Design and Use of Multi-targeting DNA Nanoswitches for Increased Sensitivity Detection of Long RNAs
This technology provides a novel method for detecting COVID-19 and potentially other virus-based diseases.
Background:
The COVID-19 pandemic created an unprecedented need for large scale diagnostic testing. Unfortunately, the pandemic also created a number of challenges for traditional in vitro diagnostic techniques. These challenges include reagent...
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen
Keywords(s): detection, DNA nanoswitches, Sensitivity, Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Diagnostics, Technology Classifications > Research Tools and Reagents
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