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Novel Cryoelectrospun Scaffolds for Tissue Engineering and Methods for Manufacturing

Methods to produce 3D nanofibrous scaffolds that closely mimic soft-tissue stromal ECM using a unique cryoelectrospinning process. Background: The extracellular matrix (ECM) comprising the proteinaceous scaffold within the connective tissue is involved in regulating the function of parenchymal tissue in organs. When that becomes stiff, or fibrotic,...
Published: 7/11/2023   |   Inventor(s): Susan Sharfstein, Yubing Xie, Pujhitha Ramesh, James Castracane, Melinda Larsen
Keywords(s): Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Screens and Assays, Campus > University at Albany

Microfluidic Intravital Window

­A self-contained device that facilitates simultaneous in vivo viewing and remotely controlled fluid delivery to the target tissue. Background: Research has led to a new understanding of how tumor microenvironment heterogeneity presents delivery barriers that hamper the effectiveness of cancer treatments. High-resolution imaging can identify,...
Published: 12/26/2023   |   Inventor(s): James Castracane, Logan Butt, Lauren Sfakis
Keywords(s): Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Imaging

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