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Injectable Hydrogel System Designed to Prolong Joint Retention in Osteoarthritis

An injectable hydrogel platform that forms a lubricious depot in the joint after a single minimally invasive injection, enabling multi-week retention and sustained release of drug-loaded nanocarriers. BACKGROUND: Osteoarthritis (OA) is a leading cause of chronic pain and disability worldwide. Current intra-articular standards of care, such as analgesics,...
Published: 9/2/2026   |   Inventor(s): Jonathan Lovell, Zachary Varrenti, Ramkumar Tiruvannamalai Annamalai, Yiting Song
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines

Stable Micelle Drug Formulations

Method for producing stable, concentrated drug micelles that reduce or eliminate surfactants from drug formulations. Background: Hydrophobic drugs comprise a substantial proportion of all pharmaceutical compounds in use today. These drugs have limited solubility in water. There are numerous strategies for addressing solubility; however, for many...
Published: 8/31/2026   |   Inventor(s): Jonathan Lovell, Wentao Song, Yumiao Zhang
Keywords(s): Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Nanotechnology, Campus > University at Buffalo

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