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Genome Edited Tumor Cells as Anti Cancer Vaccines

This novel vaccine is comprised of inactivated whole tumor cells that lack the CD47 protein, making them more susceptible to immune cells in the body Background: The immune system is designed to defend our body against pathogens and dangerous invaders. However, cancer cells possess a plethora of immune evasion mechanisms in reaction to specific...
Published: 12/28/2023   |   Inventor(s): Kaiming Ye, Sha Jin, Subhadra Jayaraman Rukmini
Keywords(s):  
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Microenvironments for Self-Assembly of Islet Organoids from Stem Cell Differentiation

Decellularized tissue-specific extracellular matrix and microenvironments for pancreatic islet organoid differentiation Background: Type 1 diabetes results from autoimmune destruction of β-cells, leading to incapable of maintaining normoglycemia in these patients. Although type 2 diabetes is caused by the peripheral resistance to insulin...
Published: 12/28/2023   |   Inventor(s): Sha Jin, Kaiming Ye, Huanjing Bi
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

pH-Insensitive Glucose Indicator Protein

Non-invasive, pH insensitive glucose biosensor for diabetes patients. Background: Diabetes mellitus is one of the major health care problems of the world, affecting millions of people worldwide, and resulting in an effort to develop noninvasive methods for fast, painless, and convenient monitoring of glucose. Currently, a variety of glucose binding...
Published: 6/19/2023   |   Inventor(s): Kaiming Ye
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Campus > Binghamton University

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