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Suppressive Molecules of Diseases with Altered IgE Regulation

 Provides a new platform for the development of diseases associated with abnormal regulation of immunoglobulin E (IgE). Background: Previous research has demonstrated that congeners of tetracycline, minocycline, and doxycycline suppress asthmatic symptoms in vivo, and immunoglobulin E (IgE) from asthmatics in vitro in a dose-dependent manner. In theory,...
Published: 7/11/2023   |   Inventor(s): Helen Durkin, Martin Bluth, Rauno Joks, Tamar Smith-Norowitz
Keywords(s): allergy, asthma, atopy, immunoglobulin E (IgE)
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Biomedical Science and Engineering

Pancreatitis Associated Proteins as a Treatment for Pancreatic Diseases

 A novel method for developing diagnostic tools and treatments for pancreatitis through the use of a truncated pancreatitis-associated protein (PAP). Background: Acute pancreatitis ranges in severity from a mild, self-limiting course treated with conservative methods, to a more aggressive variety causing sepsis, pancreatic necrosis, and hemorrhage....
Published: 7/11/2023   |   Inventor(s): Martin Bluth, Michael Zenilman
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines

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