Topical Minocycline Ointment Suppresses Allergic Skin Responses
This technology presents a topical minocycline ointment formulated to effectively suppress allergic skin responses and reduce inflammation associated with allergic reactions.
Background:
Allergic skin reactions, such as hives, rashes, and inflammation caused by insect bites or contact with allergens, present common dermatological challenges that...
Published: 6/22/2026
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Inventor(s): Rauno Joks, Helen Durkin (Deceased)
Keywords(s):
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare
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Suppression of histamine and allergen induced itch and swelling with topical minocycline cream
This invention presents a topical 2% minocycline cream that significantly reduces histamine- and allergen-induced itching and swelling, offering a novel non-steroidal treatment for allergic skin reactions.
Background:
Allergic skin reactions, characterized by itching and swelling, affect many individuals and are commonly managed with steroid-based...
Published: 6/22/2026
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Inventor(s): Rauno Joks
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare
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Use of Blood Nitric Oxide Responses as a Biomarker of Obesity and its Associated Conditions, including Allergy and Asthma
This technology offers a novel method for identifying individuals at increased risk for systemic inflammatory disorders, such as asthma, by measuring intracellular nitric oxide synthase expression in specific immune cells.
Background:
Asthma and other systemic inflammatory disorders often present challenges in effective diagnosis and management due...
Published: 6/12/2026
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Inventor(s): Rauno Joks, Maja Nowakowski, Helen Durkin (Deceased)
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Screens and Assays
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Suppressive Molecules of Diseases with Altered IgE Regulation
Provides a new platform for the development of diseases associated with abnormal regulation of immunoglobulin E (IgE). Background: Previous research has demonstrated that congeners of tetracycline, minocycline, and doxycycline suppress asthmatic symptoms in vivo, and immunoglobulin E (IgE) from asthmatics in vitro in a dose-dependent manner. In theory,...
Published: 1/30/2026
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Inventor(s): Helen Durkin (Deceased), Martin Bluth, Rauno Joks, Tamar Smith-Norowitz
Keywords(s): allergy, asthma, atopy, immunoglobulin E (IgE)
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Biomedical Science and Engineering
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