Chemically Modified Curcumins (CMCs) Their Homologues and Lower Analogues as Inhibitors of Matrix Metalloproteases (MMPs) and Pro-inflammatory Cytokines (PICs)
Novel class of compound that display biological activities equal to or better than natural curcumin, which has been used throughout history to treat a wide variety of ailments. Background: Curcumin, a principal biological compound in the popular Indian curry spice turmeric, has been used throughout history to treat a wide variety of skin, pulmonary,...
Published: 11/22/2023
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Inventor(s): Lorne Golub
Keywords(s): Medical, Technologies
Category(s): Technology Classifications > Therapeutics
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Methods of Treating and Preventing Angioedema and Vascular Leakage
Peptides and antibodies that block vascular permeability induced in angioedema patients that are new targets for treatment. Background: Angioedema associated with C1-INH deficiency is an inherited or acquired condition that affects 20 per cent of the population. The condition can be disfiguring, painful and sometimes fatal. Existing treatments primarily...
Published: 11/22/2023
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Inventor(s): Berhane Ghebrehiwet
Keywords(s): angioedema, gClqR, Medical, Monoclonal antibody, peptides, Technologies, vascular leakage
Category(s): Campus > Stony Brook University, Technology Classifications > Antibodies, Technology Classifications > Therapeutics
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Novel Bio-hybrid/Bio-functional Materials
A novel method of encapsulating microbes within crosslinked electrospun hydrogel fibers that maintain their viability. Background: Electrospinning is a process where interactions between an electrostatic field and a fluid are utilized to form nanoscale and microscale polymer fibers. These fibers can be collected to form an interconnected web of fibers,...
Published: 11/22/2023
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Inventor(s): Ying Liu, Miriam Rafailovich
Keywords(s): Medical
Category(s): Campus > Stony Brook University, Technology Classifications > Material and Composites
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