IgA Monoclonal Antibodies as a Prophylactic and Therapeutic Treatment for Dengue Virus Infection
Enables the prevention and treatment of dengue by avoiding the challenge of Antibody Dependent Enhancement. Background: Dengue virus is one of the most widespread vector-borne viral pathogens in the world. Nearly 400 million dengue virus infections occur each year, resulting in approximately 20,000 deaths. In addition, dengue-associated illness comprises...
Published: 7/11/2023
|
Inventor(s): Adam Waickman, Adam Wegman
Keywords(s): antibody, antibody therapy, biologics, biomedical, disease prevention, immunotherapy, monoclonal antibody, Technologies, viral immunology, viral pathogenesis
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Antibodies, Technology Classifications > Healthcare, Technology Classifications > Viral Vectors, Campus > Upstate Medical University
|
Methods of Treating and Preventing Angioedema and Vascular Leakage
Peptides and antibodies that block vascular permeability induced in angioedema patients that are new targets for treatment. Background: Angioedema associated with C1-INH deficiency is an inherited or acquired condition that affects 20 per cent of the population. The condition can be disfiguring, painful and sometimes fatal. Existing treatments primarily...
Published: 11/22/2023
|
Inventor(s): Berhane Ghebrehiwet
Keywords(s): angioedema, gClqR, Medical, Monoclonal antibody, peptides, Technologies, vascular leakage
Category(s): Campus > Stony Brook University, Technology Classifications > Antibodies, Technology Classifications > Therapeutics
|
Monoclonal Antibody, Anti Ft LVS LpnA/Tu14 Clone 164
An intracellular bacterium that can initiate the human response to Tularemia Background: Francisella tularensis is an intracellular, gram-negative bacterium that invades macrophages and initiates the human immune response. Technology Overview: Tularemia, commonly known as ?rabbit fever? can be communicated across several species including;...
Published: 2/28/2024
|
Inventor(s): Jorge Benach, Anne Savitt
Keywords(s): Anti Ft LVS LpnA/Tul4 Clone 164, Biological or Antibody, Monoclonal antibody, Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Antibodies, Technology Classifications > Research Tools and Reagents
|