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Therapeutic backbone and scaffold modification in the physiological environment

This technology enables precise, water-based chemical modification of proteins at their C-terminus using a single, easily removable reagent, preserving protein structure and function and allowing attachment of diverse functional groups for therapeutic, research, and diagnostic applications. Background: Proteins and polypeptides play a central role...
Published: 12/19/2025   |   Inventor(s): Qiang Zhang
Keywords(s): antibody therapy, GLP-1 secretion, Insulin, protein engineering, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering

Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium

Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 10/24/2025   |   Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

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