Targeting Hypoxia-inducible factor 2alpha in cancer
This technology offers a novel approach for new cancer treatments based on inhibiting HIF2α-related processes.
Background:
Hypoxia-inducible factor 2α (HIF2α) transcription factor is involved in the adaptation of cancer cells (including clear cell renal cell carcinoma (ccRCC)) to low oxygen conditions (hypoxia). It plays a role...
Published: 6/15/2026
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Inventor(s): Mehdi Mollapour, Gennady Bratslavsky, Dimitra Bourboulia, Mark Woodford, John Chisholm
Keywords(s): cancer, cancer therapy, cell proliferation, regulation of transcriptional dynamics, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines
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