ABI1 Regulates Transcriptional Activity of Androgen Receptor by Novel DNA and AR Binding Mechanism
Provides new pathways for biomarkers and drug discovery for cancer patients.
Background:
The gene Abelson interactor protein-1 (ABI1) encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal...
Published: 10/24/2025
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Inventor(s): Leszek Kotula, Alaji Bah, Dominique Frueh
Keywords(s): DNA, regulation of transcriptional dynamics, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines
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