Targeting RNA Polymerase I Protein–Protein Interfaces Using Peptide Inhibitors:
A Computational Strategy Powered by PepTelligence, a Comprehensive Peptide Scoring System
PepTelligence is an innovative computational tool designed to evaluate and optimize therapeutic peptides by integrating multiple biochemical and pharmacological factors into a unified scoring system.
Background:
The development of PepTelligence addresses a significant challenge in peptide drug discovery: the absence of a comprehensive evaluation...
Published: 2/25/2026
|
Inventor(s): Maryam Kabiri, Bruce Knutson
Keywords(s): multi-parameter scoring, peptide design, peptide drug discovery, peptide scoring system, structural bioinformatics, Technologies, therapeutic peptides
Category(s): Technology Classifications > Computer Software, Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
|
Method for Sampling Terahertz Pulses in the Time-Domain Using Modulated Difference-Frequency in the Repetition Rates of Femtosecond Lasers
050-9317 Portable Handheld Spectral Reflection (PHASR) Scanner to Allow THz Time-Domain Spectroscopic (THz-TDS) Imaging of Burn Wounds
A handheld terahertz (THz) spectroscopy and 3D imaging device designed for noninvasive evaluation of burn injury severity
Background:
Burn injuries pose a substantial public health challenge, leading to hundreds...
Published: 2/19/2026
|
Inventor(s): Mohammad Arbab, Zachery Harris
Keywords(s):
Category(s): Technology Classifications > Computer Software, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Optics and Photonics, Campus > Stony Brook University
|
HistoTME: an AI tool for prediction of the tumor microenvironment molecular composition from histopathology images
HistoTME is an AI software that predicts the tumor microenvironment’s molecular makeup from standard pathology images, helping identify lung cancer patients likely to benefit from immunotherapy without needing costly molecular tests.
Background:
The tumor microenvironment (TME) plays a crucial role in the progression and treatment response...
Published: 2/3/2026
|
Inventor(s): Tamara Jamaspishvili, Sushant Patkar, Alex Chen, Stephanie Harmon, Ismail Turkbey
Keywords(s): artificial intelligence, cancer, computational biology, digital image processing, disease diagnosis, Technologies
Category(s): Technology Classifications > Computer Software, Campus > Upstate Medical University, Technology Classifications > Medical Imaging
|
App for perinatal mood and anxiety disorder intervention
A mobile digital application that uses a cognitive behavioral theory (CBT) model to help individuals struggling with perinatal mood and anxiety disorders.
Background:
Approximately 10-24% of women report peripartum mood and anxiety disorders (PMADs) as a complication of pregnancy. Untreated PMADs have devastating outcomes on the physical and mental...
Published: 1/26/2026
|
Inventor(s): Seethalakshmi Ramanathan, Rahul Bhatt
Keywords(s): anxiety, CBT, depression, perinatal, Technologies
Category(s): Technology Classifications, Technology Classifications > Computer Software
|
3D CT Reconstruction from Few X-rays
A technology that reconstructs CT images by integrating implicit neural representation and conditional diffusion models
Background:
Computed Tomography (CT) imaging faces a persistent challenge in balancing the need for high-quality, accurate three-dimensional reconstructions with the imperative to minimize patient radiation exposure and scanning...
Published: 10/15/2025
|
Inventor(s): Arie Kaufman, Gaofeng Deng
Keywords(s):
Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Technology Classifications > Computers, Technology Classifications > Medical Imaging, Campus > Stony Brook University
|
PELOTON code
A time-dependent, three-dimensional pellet ablation code developed to simulate the physical processes in thermonuclear fusion devices
Background:
In magnetic confinement fusion devices, precise control of pellet fueling and disruption mitigation is critical, yet predicting how cryogenic pellets interact with hot plasma remains a major challenge....
Published: 10/6/2025
|
Inventor(s): Roman Samulyak
Keywords(s):
Category(s): Technology Classifications > Computer Software, Campus > Stony Brook University
|
Machine Learning Diagnosis of In Vivo Tissues by Extracting Tissue-Energy Characteristic Features from Non-Invasively Acquired Computed Tomographic Data
The technology features enable ML models to more accurately classify indeterminate pulmonary nodules and colorectal polyps
Background:
Computed tomography (CT) is a widely used imaging tool for early detection of cancers such as lung and colorectal cancer. However, current low-dose CT screening protocols suffer from high false positive rates, particularly...
Published: 9/19/2025
|
Inventor(s): Jerome Liang
Keywords(s):
Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Technology Classifications > Diagnostics, Technology Classifications > Healthcare IT, Technology Classifications > Information Technology, Technology Classifications > Medical Imaging, Campus > Stony Brook University
|
VolMoVis: Real-Time Volumetric Motion Visualization with 4D Tomographic Reconstruction
A 4D tomographic reconstruction algorithm that offers high temporal resolution for real-time motion visualization in radiation therapy.
RSS.HDBackground> Background: <
Cone beam computed tomography (CBCT) is an essential imaging modality use in radiation therapy procedures. CBCT works by taking 2D x‑ray images from multiple angles, which are...
Published: 9/4/2025
|
Inventor(s): Arie Kaufman, Gaofeng Deng
Keywords(s):
Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Technology Classifications > Healthcare IT, Technology Classifications > Information Technology, Technology Classifications > Medical Imaging, Campus > Stony Brook University, Technology Classifications > Computers
|
MotionGen
Planar Linkage and Mechanism Design and Simulation App for web, Android, and iOS
RSS.HDBackground> Background: <
Despite major advances in AI and robotics, the design of motion systems, such as one- and multi-degrees-of-freedom linkage mechanisms, remains an outdated, manual bottleneck. Engineers routinely spend up to 40% of their total design...
Published: 7/29/2025
|
Inventor(s): Anurag Purwar*
Keywords(s):
Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Campus > Stony Brook University
|
SeeMe: A novel tool for measuring and detecting human consciousness
An objective and quantifiable tool that can be used to measure the level of human consciousness in comatose patients
Background:
Assessing the functional state of the brain and predicting recovery of consciousness following acute brain injury (ABI) remains a major unsolved clinical problem. Currently, behavioral measures of recovery with scoring...
Published: 4/23/2025
|
Inventor(s): Sima Mofakham, Charles Mikell, Xi Cheng
Keywords(s):
Category(s): Campus, Technology Classifications > Computer Software, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Campus > Stony Brook University
|