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Vaccine to Prevent Otitis Media and Infections in COPD

Moraxella catarrhalis antigen AfeA immunization of chronic obstructive pulmonary disease (COPD) patients. Chronic obstructive pulmonary disease (COPD) is a progressive and irreversible lung disease characterized by chronic inflammation reduced air flow. It is associated with smoke inhalation (typically from cigarettes or cooking fires) and air pollution...
Published: 1/9/2018   |   Inventor(s): Timothy Murphy, Aimee Brauer
Keywords(s): Technology
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > University at Buffalo

Novel Vaccine Antigens for Moraxella Catarrhalis

Several vaccine targets developed to Moraxella catarrhalis, a pathogen found in otitis media (middle ear infection) and chronic pulmonary obstruction disease (COPD). Otitis media (OM), or middle ear infection, is one of the most common reasons for pediatric office visits. An estimated 30 million office visits can be attributed to OM every year. Eighty...
Published: 5/22/2014   |   Inventor(s): Timothy Murphy, Charmaine Kirkham, Alan J Lesse
Keywords(s): Technology
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > University at Buffalo

A Vaccine to Prevent Infection by Nontypeable Haemophilus Influenzae infection

A vaccine to non-typeable Haemophilus influenzae (NTHi) based on OMP P2 with demonstrated effectiveness against greater than half of all tested NTHi strains.Currently, there is no effective vaccine to prevent infection by non-typeable Haemophilus influenzae (NTHi), a leading cause of otitis media as well as a number of other upper respiratory tract...
Published: 5/21/2014   |   Inventor(s): Timothy Murphy, Thomas Hiltke, Sanjay Sethi
Keywords(s): Technology
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > University at Buffalo

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