A Novel 14-3-3 Inhibitor to treat chronic pain
Inhibitor of 14-3-3 showing reduced ion-channel excitability in pain-sensing neurons and decreased pain behavior in mice, with no evidence of acute toxicity
Background:
14-3-3 proteins are small (28-30 kDa) acidic, highly-conserved proteins that comprise a family of seven isoforms in mammals. They are found throughout the cell and function in signaling...
Published: 10/8/2026
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Inventor(s): Arindam Bhattacharjee, Rasheen Powell
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines
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Methods and Apparatus to Allocate Physical Qubits to Support Distributed Quantum Error Correction (QEC) Codes
A novel distributed quantum computing system and several methods of qubit allocation to enhance scalability to achieve large-scale fault-tolerant quantum systems
Background:
Quantum Processing Units (QPUs) are specialized components of Quantum Computing systems which leverage the principles of quantum mechanics to perform complex calculations. Current...
Published: 10/7/2026
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Inventor(s): Chunming Qiao, Shahram Babaie
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Quantum Computing, Technology Classifications > Computers
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High-Density Neurostimulation System
High-density cluster electrode technology that enables a high degree of scalability and customization for neurostimulation applications
Background:
Existing skin-surface neurostimulation is achieved by a single electrode that performs bulk stimulation on the entire tissue in the neurostimulation area. It does not have the capability to control the...
Published: 10/7/2026
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Inventor(s): Filip Stefanovic, Albert Titus
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Assistive Technology, Technology Classifications > Medical Devices
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Novel Small Molecule Anabolic Agents for Osteoporosis
Analogs of a naturally occurring phytoestrogen that hold promise for the treatment of osteoporosis and other conditions impacting peri- and post-menopausal women
Background:
Menopause significantly speeds bone loss and increases the risk of osteoporosis, a condition characterized by decreased bone mineral density and which impacts more than 200M people...
Published: 10/7/2026
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Inventor(s): Bhaskar Das, Hiranmoy Das
Keywords(s): Featured, Pharmaceutical, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
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Potent Melatonin Receptor Ligands
Novel compounds for modulation of MT1 and/or MT2 receptor activity
Background:
Melatonin is an indoleamine hormone produced by the pineal gland. It is known primarily for its critical importance in regulating sleep promotion and circadian rhythms, however melatonin has also been implicated in a broad range of unique functions. These include: regulation...
Published: 10/7/2026
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Inventor(s): Margarita Dubocovich, Andrew Tsotinis, Vasiliki Tsalakidou, Aikaterini Sakellaropoulou, Ioannis Papanastasiou, Marina Boniakou
Keywords(s): Featured, Pharmaceutical, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines
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Ga₂O₃ Vertical MOSFET for Enhanced Power Management
A vertical trench MOSFET using a unique in-situ Mg-doped current blocking layer to enable high-voltage operation with enhanced efficiency and robustness in power electronic devices.
Background:
This technology addresses the need for high-voltage power devices suitable for grid and traction applications, overcoming the limitations of traditional silicon-based...
Published: 10/7/2026
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Inventor(s): Uttam Singisetti, Hongping Zhao, Sudipto Saha, Lingyu Meng, Dong Yu
Keywords(s): Featured, Semiconductor and Microprocessing, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Energy, Technology Classifications > Electronics
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Novel Antifungal Agents with Dual Mechanism of Action
With a clear and growing unmet need, a novel mechanism of action, and demonstrated in vitro superiority over current standard-of-care agents, these novel boron-based antifungal agents represent a compelling early-stage opportunity with significant commercial and public health relevance.
Background:
Invasive fungal infections caused by opportunistic...
Published: 10/7/2026
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Inventor(s): Bhaskar Das, Joshua Nosanchuk, Daniel Miranda
Keywords(s): Chemistry, Featured, Healthcare, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
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Tools to Predict Clinical Immunogenicity
In vitro tools for predicting clinical immunogenicity of subcutaneously administered antigens, whether for therapeutic or prophylactic applications.
Background:
Immunogenicity, the propensity of a product to elicit an immune response to itself or related structures, may be desirable (e.g. vaccine candidates) or undesirable...
Published: 8/31/2026
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Inventor(s): Sathy Balu-Iyer, Aditi Venkatesh
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Fluorescent Peptides for Membrane Tension Reporting and Biomarkers
A peptide-based probe technology that enables real-time, non-invasive fluorescent detection and quantitation of cell membrane tension.
Background:
The 2021 Nobel Prize in Physiology or Medicine was awarded for the discovery of Piezo channels, mechanosensitive ion channels that respond to cell membrane tension, translating mechanical force directly...
Published: 10/15/2026
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Inventor(s): Thomas Suchyna, Sergei Sukharev
Keywords(s): Featured, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Biological Materials
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Language-Agnostic Voice Biomarker Platform for Early Detection of Alzheimer’s Disease and Related Dementias (GloVoAD)
This technology enables early, non-invasive detection of Alzheimer’s disease and related dementias using a large-scale multilingual voice dataset and language-agnostic AI models that analyze vocal biomarkers without relying on speech transcription.
BACKGROUND:
Early detection of Alzheimer’s disease and related dementias (ADRD) remains...
Published: 8/31/2026
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Inventor(s): Wei Bo, Wenyao Xu, Aditya Challamarad, Harry Lin
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Diagnostics
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