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Development of a Pediatric Tuberculosis Diagnostic Test

A lipoprotein diagnostic marker for TB disease ideal for a simple diagnostic assay from a finger prick blood or serum Background: The inadequate sensitivity of available organism-based TB diagnostic tools in children, the wide spectrum of disease observed in children, and the non-specific signs and symptoms especially in young and HIV-children,...
Published: 2/28/2024   |   Inventor(s): Nicole Sampson, Xinxin Yang
Keywords(s): antibody, biomarker, diagnosis, ELISA, modified LDL, Technologies, tuberculosis
Category(s): Campus > Stony Brook University, Technology Classifications > Antibodies, Technology Classifications > Diagnostics

Novel Drugs for the Treatment of Tuberculosis

Compounds that increase TB therapy efficacy through a mechanism of action for increased tolerance and decreased therapy duration. Background: One third of the world's population is infected with tuberculosis (TB). In 2014, there were 1.5 million TB related deaths. The current recommended treatment regimen for TB begins with a two-month intensive therapy...
Published: 6/5/2023   |   Inventor(s): Nicole Sampson, Xinxin Yang, Tianao Yuan
Category(s): Campus > Stony Brook University, Technology Classifications > Drug Design and/or Synthesis

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