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6-azasteroids with unique activity in mycobacteria

The compound functions as potentiators of several anti-tuberculosis drugs RSS.HDBackground> Background: < One third of the world’s population is infected with tuberculosis (TB). In 2014, there were 1.5 million TB related deaths. There are drugs to combat the bacteria by attacking the bacteria directly. The current recommended treatment...
Published: 2/4/2025   |   Inventor(s): Nicole Sampson, Joshua Werman, Tianao Yuan
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Drug Design and/or Synthesis, Campus > Stony Brook University

Novel Drugs for the Treatment of Tuberculosis

Compounds that increase TB therapy efficacy through a mechanism of action for increased tolerance and decreased therapy duration. Background: One third of the world's population is infected with tuberculosis (TB). In 2014, there were 1.5 million TB related deaths. The current recommended treatment regimen for TB begins with a two-month intensive therapy...
Published: 8/27/2024   |   Inventor(s): Nicole Sampson, Xinxin Yang, Tianao Yuan
Keywords(s):  
Category(s): Campus > Stony Brook University, Technology Classifications > Drug Design and/or Synthesis

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