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An anti-capsular antibody that cross protects against clade 1 Carbapenem-resistant Klebsiella pneumoniae

 A monoclonal antibody that exhibits cross-protective efficacy against multiple ST258 CR-Kp strains RSS.HDBackground> Background: < Therapeutic monoclonal antibodies (mAbs) have emerged as a dominant therapeutic modality to treat cancer, immune disorders, and infectious diseases such as high-mortality Carbapenem-resistant Klebsiella pneumoniae...
Published: 2/4/2025   |   Inventor(s): Kasturi Banerjee, Bettina Fries, Michael Motley
Keywords(s):  
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Antibodies, Campus > Stony Brook University

Novel Monoclonal Antibodies to Treat Carbapenem-Resistant Klebsiella Pneumoniae Infections

 These mABs elicit phagocytic activity and protective immune response to clear bacteria from infected mice. Background: Carbapenem-resistant K.pneumonia (CR-Kp) strains are a major threat worldwide due to the difficult to treat. Lack of new antibiotics in pipeline and the emergence of resistance to the last-resource antibiotics has resulted in an urgent...
Published: 11/22/2023   |   Inventor(s): Bettina Fries, Elizabet Diago Navarro
Keywords(s): Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Antibodies, Technology Classifications > Diagnostics, Technology Classifications > Therapeutics

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