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Small Molecule Inhibitors for Alzheimer's Immunotherapy

Pan-SHIP1/2 inhibitors enhance phagocytosis of dead neurons and amyloid beta by microglia. Background: The beta-amyloid (1-42) peptide fragment is a crucial component of beta-amyloid debris that forms plaques in Alzheimer's Disease, playing a significant role in disease pathology and cognitive decline. Increased amyloid deposits and tau tangles...
Published: 7/11/2023   |   Inventor(s): William Kerr, Chiara Pedicone
Keywords(s): TAF, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines

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