Use of 2-Hydroxyoleic Acid for the Treatment of Systemic Lupus Erythematosus and Other Immune Pathologies
A novel B cell tolerance pathway activated by the lipid enzyme sphingomyelin synthases 2 (SMS2).
Background:
Autoimmune diseases such as Systemic Lupus Erythematosus are chronic, painful and debilitating. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have some form of lupus. The...
Published: 4/1/2025
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Inventor(s): Chongmin Huan, Christopher Roman, Peiqi Ou
Keywords(s): TAF, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Therapeutics and Vaccines
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Drug Discovery Based on Surface-Enhanced Raman Spectroscopy (SERS)
Enables drug discovery without introducing modifications to the molecules, while lowering costs by requiring only small amounts of the tested molecules.
Background:
Surface-enhanced Raman spectroscopy (SERS) is a novel, label-free, sensitive, specific, fast, and relatively inexpensive tool for drug discovery. It offers the potential to detect and...
Published: 4/1/2025
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Inventor(s): Igor Lednev, Lamyaa Almehmadi, Jia Sheng
Keywords(s): Raman spectroscopy, RNA, RNA chemistry, TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Antibodies, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Urban Blight Monitoring System
Simplifies and automates the process of monitoring and assessing urban blight. Background: Urban blight is defined as "the process whereby a previously functioning city, or part of a city, falls into disrepair and decrepitude" (Wikipedia). Keeping track of the progress of urban blight requires time and resources to collect and analyze data. Cities...
Published: 4/1/2025
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Inventor(s): Derek Werthmuller, James Costello, Varun Chandrasekar Narayanan
Keywords(s): TAF, Technologies
Category(s): Technology Classifications > Information Technology, Campus, Campus > University at Albany
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Determining Bloodstain Age Using Raman Spectroscopy
A novel and non-destructive method of determining the age of an evidentiary bloodstain using Raman Spectroscopy. Background: Forensic investigators are members of law enforcement that help secure a crime scene and collect evidence. When the evidence involves blood, the age of that blood is a critical piece of information investigators need to identify...
Published: 4/1/2025
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Inventor(s): Igor Lednev
Keywords(s): TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
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Gel Electrophoresis Sensor and Controller
Compatible with both agarose (horizontal) and polyacrylamide (vertical) gel electrophoresis systems. Background: Electrophoresis gels are widely used in biotechnology for analyzing biomolecular sample materials such as proteins and nucleic acids. Electrophoresis involves the migration of electrically charged particles in a gel solution or suspension...
Published: 4/1/2025
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Inventor(s): Papa Asare-Okai, Rabi Musah, Tony Hoang
Keywords(s): TAF, Technologies
Category(s): Technology Classifications > Research Tools and Reagents, Campus > University at Albany
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Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) Spectroscopy for Gunshot Residue Analysis
Quickly and automatically detects a variety of gunshot residue types. RSS.HDBackground> Background: < Gunshot residue (GSR) particles are the chemical remains of ammunition expelled from a firearm discharge. GSR can assist investigators in shooting incident reconstruction. Recovery, detection, and preservation of these discharge samples are...
Published: 4/1/2025
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Inventor(s): Igor Lednev, Justin Bueno
Keywords(s): TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Identification of Body Fluids Using Raman Spectroscopy
A one-step confirmatory test to identify forensic body fluid samples.
Technology Overview:
This simple, non-destructive method for positive identification of all forensic body fluid types, is based on Raman Spectroscopy,a light scattering phenomenon that provides a unique molecular vibrational signature of a material. The patented technology...
Published: 4/1/2025
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Inventor(s): Igor Lednev, Kelly Virkler
Keywords(s): 3D printing, blood, evidentiary sample, fluorescence spectroscopy, forensics, oral epithelial cells, Raman microscopy, Raman spectroscopy, saliva, semen, sperm, sweat, TAF, vaginal epithelial cells, vaginal fluid
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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Semiconductor Annealing Monitoring
Provides real-time, in-situ monitoring of conductivity change in a doped semiconductor wafer that is being subjected to pulsed microwave annealing.
Background:
Certain semiconductor wafers are manufactured via a process called doping. During this process, a material (the dopant) is introduced into the semiconductor crystal to change its electrical...
Published: 4/1/2025
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Inventor(s): Fatemeh Shahedipour-Sandvik, Vincent Meyers
Keywords(s): biomedical, chemistry, microsystem, semiconductors, TAF, Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Electronics, Technology Classifications > Materials and Chemicals
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Small Molecule Inhibitors for Alzheimer's Immunotherapy
Pan-SHIP1/2 inhibitors enhance phagocytosis of dead neurons and amyloid beta by microglia. Background: The beta-amyloid (1-42) peptide fragment is a crucial component of beta-amyloid debris that forms plaques in Alzheimer's Disease, playing a significant role in disease pathology and cognitive decline. Increased amyloid deposits and tau tangles...
Published: 4/1/2025
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Inventor(s): William Kerr, Chiara Pedicone
Keywords(s): TAF, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines
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Components for Generating Orbital Angular Momentum in Electromagnetic Waves
A device that seamlessly extends 4G communications data rates into anticipated 5G data rate ranges. Background: Electromagnetic (EM) waves are used to provide modern telecommunications for transmitting and receiving data. Conventional modes of communication involve some form of modulation, such as amplitude, frequency and pulse-width modulation. Controlling...
Published: 4/1/2025
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Inventor(s): Patanjali Parimi, Ashutosh Patri
Keywords(s): #SUNYresearch, TAF, Technologies, wireless technology
Category(s): Technology Classifications > Electronics, Technology Classifications > Engineering, Campus > SUNY Oswego
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