Kcnh2 Mutant Rabbit
Genetic animal model of Long QT Syndrome Type-2 (LQT2) reproduces the neuro-cardiac pathologies and high risk of sudden death seen in people with LQT2, and provides a platform for advanced research and drug testing.
Background:
Long QT Syndrome Type-2 (LQT2) is due to genetic variants in the Kcnh2 gene, which encodes a potassium channel protein that...
Published: 6/24/2026
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Inventor(s): David Auerbach
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Research Tools and Reagents
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Procedure for Pre-Clinical Continuous EEG/ECG Monitoring
This technology introduces a novel surgical procedure, custom implant, and wiring harness for continuous electroencephalogram (EEG) and electrocardiogram (ECG) monitoring in conscious unrestrained animals. The animal is chronically implanted with subdermal electrodes and connected to a durable wiring system to capture high-quality physiological data....
Published: 6/24/2026
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Inventor(s): David Auerbach, Kyle Wagner, Laura Williams
Keywords(s): animal models, animal studies, bioengineering, biomedical science, biosensor, electrocardiogram, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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Development of an Out-of-Hospital ECG-Based Diagnostic Biomarker to Distinguish Epileptic vs. Functional/Dissociative Seizures
This innovation presents a machine learning-based diagnostic tool that uses an electrocardiogram (ECG) signal to accurately distinguish between convulsive epileptic seizures and functional/dissociative seizures.
Background:
Diagnosing epileptic seizures (ES) versus functional/dissociative seizures (FDS) is complex and traditionally depends on long-term...
Published: 6/24/2026
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Inventor(s): David Auerbach, Justin Ryan, Kyle Wagner
Keywords(s): biomarkers, epilepsy, seizures, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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