Hand-held Glucometer based pathogen and other biomarker detection using RNA switches
This technology uses engineered RNA switches and CRISPR to detect various biomarkers, converting their presence into glucose that can be measured with a standard handheld glucometer, enabling rapid, low-cost, and versatile point-of-care diagnostics.
Background:
Molecular diagnostics is a rapidly evolving field that plays a crucial role in the detection...
Published: 7/9/2026
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Inventor(s): Mehmet Yigit, Emmett Hanson, Mahla Lashkari, Natalie Connell
Keywords(s): biomarkers, diagnostics, RNA-switch, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Development of an Out-of-Hospital ECG-Based Diagnostic Biomarker to Distinguish Epileptic vs. Functional/Dissociative Seizures
This innovation presents a machine learning-based diagnostic tool that uses an electrocardiogram (ECG) signal to accurately distinguish between convulsive epileptic seizures and functional/dissociative seizures.
Background:
Diagnosing epileptic seizures (ES) versus functional/dissociative seizures (FDS) is complex and traditionally depends on long-term...
Published: 6/29/2026
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Inventor(s): David Auerbach, Justin Ryan, Kyle Wagner
Keywords(s): biomarkers, epilepsy, seizures, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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Bi-Directional mTOR Blockade and Companion Biomarkers of Flare and Predictors of Therapeutic Efficacy in SLE
Novel therapeutic intervention targeting mTOR pathways combined with companion biomarkers enables personalized treatment of SLE and its liver complications.
Background:
Systemic lupus erythematosus (SLE) is a chronic, heterogeneous autoimmune disorder marked by dysregulated immune activity, systemic inflammation, and progressive damage across multiple...
Published: 6/29/2026
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Inventor(s): Andras Perl
Keywords(s): biomarker diagnostics, biomarkers, drug efficacy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
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Algorithm for Identifying Images of Fluorescently-Labeled Cells
Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more.
Background:
Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...
Published: 6/11/2026
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Inventor(s): Alex Valm, Yunlong Feng
Keywords(s): bacterial cells, bacterial infection, bioengineering, biofilm control, bioinformatics, biomarker diagnostics, biomarkers, cancer, cell biology, computational biology, dental, diagnostics, digital image processing, fluorescence, fluorescence spectroscopy, gene expression analysis, image analysis, image processing, machine learning, medical imaging, microbial pathogenesis, personalized medicine, RNA, saliva, scanning microscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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Stratification Method that Determines the Prognosis of Breast Cancer at a Personalized Level
A reliable, accurate, and versatile method for determining the prognosis of primary breast cancer tumors post-surgery.
Background:
Breast cancer is the second most common type of cancer in women in the United States, after skin cancer. On rare occasions, it can also occur in men. According to the American Cancer Society, nearly 300,000 new cases...
Published: 1/29/2026
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Inventor(s): Vladimir Kuznetsov, Leszek Kotula
Keywords(s): biomarkers, biostatistics, breast cancer, diagnostics, functional genomics, gene expression analysis, oncology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
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