Sparse Poisson Regression Approach for Unmixing Images of Fluorescently-Labeled Cells
Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more.
Background:
Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...
Published: 2/12/2024
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Inventor(s): Alex Valm, Yunlong Feng
Keywords(s): bacterial cells, bacterial infection, bioengineering, biofilm control, bioinformatics, biomarker diagnostics, biomarkers, cancer, cell biology, computational biology, dental, diagnostics, digital image processing, fluorescence, fluorescence spectroscopy, gene expression analysis, image analysis, image processing, machine learning, medical imaging, microbial pathogenesis, personalized medicine, RNA, saliva, scanning microscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors
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Enhancing Responses to Chemical Interventions by Programmed Introduction of Multiple Refractory Periods
A medical device that can deliver multiple, brief intervention doses over a 24 hour period that improves cell biologic responses. Background: The ability of any exogenous intervention, be it physical or chemical in nature, to influence cell activity is markedly enhanced by incorporating a rest period between stimulation periods within any given...
Published: 6/5/2023
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Inventor(s): Clinton Rubin
Keywords(s): Adaptation, Adipogenesis, Adult Stem Cells, Augmentation, Bioelectrical, Bioengineering, Biological, Biomechanical, Biomedical or Biotechnology, Device, Enhancement, Intervention, Mechanical, Mesenchymal Stem Cells, Non-invasive, Osteogenesis, Pharmaceutical, Repair, Stimulation, Technologies, Timing, Tissue
Category(s): Campus > Stony Brook University, Technology Classifications > Medical Devices, Technology Classifications > Therapeutics
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