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Novel Compounds and Methods for Treating Invasive Fungal Infections

Compounds that decrease the synthesis of glucosylceramide, a sphingolipid that promotes fungal infection Background: With the increasing number of immunodeficient subjects and the increase of the lifespan of these subjects due to the advance in medicine, there has been a concomitant rise in the number of cases of life-threatening fungal infections....
Published: 6/5/2023   |   Inventor(s): Maurizio Del Poeta, Visesato Mor
Keywords(s): antifungal, fungal infection, glucosylceramide, sphingolipid, Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Therapeutics

Fungal Glucosylceramide as a Vaccine for Fungal Infections

Purified lipid extracted from nonpathogenic fungal cells as an antigen to stimulate the host immunity Background: Fungal infections pose a significant threat to public health. Fungi are common in the environment, as they can thrive in soil, on plants and trees, and on animate objects, including human skin. Despite the availability of antifungal...
Published: 11/22/2023   |   Inventor(s): Maurizio Del Poeta, Visesato Mor
Keywords(s): cerebroside, fungal infection, glucosylceramide, sphingolipid, Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Therapeutics

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