Search Results

2 Results
for "joseph+balthasar"
Use Advanced Search
Sort By:

Compositions and Methods for Increased Circulation Half-Life

Single domain antibody composition that enable half-life extension and increased blood:tissue ratios. Background: While strategies such as PEGylation (PEG, polyethylene glycol), albumin binding, and Fc-fusion have been employed to extend the half-life of biological and pharmaceutical agents, there remains a need for additional strategies that not...
Published: 2/2/2024   |   Inventor(s): Brandon Bordeau, Joseph Balthasar, Toan Nguyen
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Antibodies, Technology Classifications > Therapeutics and Vaccines

Targeted delivery of matrix-modulating enzymes

­For enhanced monoclonal antibody uptake and distribution in solid tumors. Background: Penetration of anti-tumor therapies is often limited by the tumor microenvironment, which can include a high density of extracellular matrix as well as elevated interstitial fluid pressure, both of which create a barrier to distribution. It is well established...
Published: 2/2/2024   |   Inventor(s): Joseph Balthasar, Brandon Bordeau
Keywords(s): Technologies
Category(s): Technology Classifications, Technology Classifications > Antibodies, Technology Classifications > Therapeutics and Vaccines, Campus > University at Buffalo

Search SUNY Technologies

Trending Searches

Latest Technologies