Raman Spectroscopy for Probing Encapsulation of mRNA in Lipid Nanoparticles
This technology uses deep ultraviolet Raman spectroscopy and advanced data analysis to quickly and non-destructively measure how much mRNA is unencapsulated in lipid nanoparticles, improving quality control for mRNA vaccines and therapeutics without chemical labels.
Background:
Messenger RNA (mRNA) therapeutics, particularly those delivered via lipid...
Published: 6/12/2026
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Inventor(s): Igor Lednev, Alexander Shekhtman, Sergei Reverdatto, Sila Jin, Young Mee Jung
Keywords(s): mRNA, Raman spectroscopy, spectroscopy, statistical analysis, Technologies, therapeutics, vaccines
Category(s): Campus > University at Albany, Technology Classifications > Gene Therapy
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