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Raman Spectroscopy for Testing Stability of RNA-based Vaccines and Drugs

A fast, less expensive, and more reliable method for assessing mRNA degradation in vaccines, that can also be used as a tool for the development of new RNA-based therapeutics. Background: The development of mRNA-based vaccines for COVID-19 offers the potential for a new medical paradigm based on RNA technology. Unfortunately, these drugs require...
Published: 2/12/2024   |   Inventor(s): Igor Lednev, Alexander Shekhtman, Lamyaa Almehmadi, Sergei Reverdatto
Keywords(s): drug stability, mRNA, mRNA stability, Raman spectroscopy, RNA, Technologies, vaccine stability, vaccines
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors

Drug Discovery Based on Surface-Enhanced Raman Spectroscopy (SERS)

Enables drug discovery without introducing modifications to the molecules, while lowering costs by requiring only small amounts of the tested molecules. Background: Surface-enhanced Raman spectroscopy (SERS) is a novel, label-free, sensitive, specific, fast, and relatively inexpensive tool for drug discovery. It offers the potential to detect and...
Published: 3/12/2024   |   Inventor(s): Igor Lednev, Lamyaa Almehmadi, Jia Sheng
Keywords(s): Raman spectroscopy, RNA, RNA chemistry, TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Antibodies, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines

Determining the Donor Age Based on Raman Spectroscopy of a Bloodstain

Novel methodology helps forensic investigators determine victim's age from bloodstains. Background: In the absence of a body at a crime scene, forensic investigators must rely on whatever biological material is left behind to determine the sex, race, and age of perpetrators and victims. That often means analyzing stains like blood, sweat, and...
Published: 1/22/2024   |   Inventor(s): Igor Lednev
Keywords(s): biological, blood, blood based technology, crime scene analysis, DNA, evidence collection, forensic tool, forensics, laboratory blood test, Raman spectroscopy, raman system, spectroscopy, TAF, Technologies, trace evidence
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics

Identification of Body Fluids Using Raman Spectroscopy

A one-step confirmatory test to identify forensic body fluid samples. Technology Overview: This simple, non-destructive method for positive identification of all forensic body fluid types, is based on Raman Spectroscopy,a light scattering phenomenon that provides a unique molecular vibrational signature of a material. The patented technology...
Published: 3/12/2024   |   Inventor(s): Igor Lednev, Kelly Virkler
Keywords(s): 3D printing, blood, evidentiary sample, fluorescence spectroscopy, forensics, oral epithelial cells, Raman microscopy, Raman spectroscopy, saliva, semen, sperm, sweat, TAF, vaginal epithelial cells, vaginal fluid
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany

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