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Genetically Engineered AAV Rep for Gene Targeting and rAAV Production

A genetic element within the Rep gene sequence, which is inhibitory to Ad replication. Background: Gene therapy strategies have exploited lenti or retro –viral approaches for long-term gene replacement, however, their clinical applications remain limited because of potential for viral-associated oncogenesis. Recently, gene therapy strategies...
Published: 6/7/2012   |   Inventor(s): Wadie Bahou, Patrick Hearing, Varsha Sitaraman
Keywords(s): Technology
Category(s): Therapeutics, Gene Therapy and Viral Vectors, Research Tools and Reagents, Campus > Stony Brook University

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