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Biliverdin IXβ Reductase

Developing first-in-class therapy for patients with thrombocytopenia. Background: Thrombocytopenia is a medical condition characterized by low platelet counts. Thrombocytopenia can be brought on as a result of a separate disorder such as leukemia, an immune system problem or it can be an adverse result of taking medication, such as chemotherapy. Symptoms...
Published: 8/27/2024   |   Inventor(s): Wadie Bahou, Song Wu
Keywords(s): Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Therapeutics

Genetically Engineered AAV Rep for Gene Targeting and rAAV Production

Researchers at Stony Brook University have identified a genetic element within the Rep gene sequence which is inhibitory to Ad replication. Background: Gene therapy strategies have exploited lenti or retro viral approaches for long-term gene replacement, however, their clinical applications remain limited because of potential for viral-associated...
Published: 9/9/2024   |   Inventor(s): Wadie Bahou, Patrick Hearing, Varsha Sitaraman
Keywords(s): Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Gene Therapy and Viral Vectors, Technology Classifications > Therapeutics, Technology Classifications > Research Tools and Reagents

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